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Lupus
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Neonatal Lupus Erythematosus with Multisystem Organ Involvement Preceding Cutaneous Lesions

Eduardo Fonseca

Department of Dermatology, Hospital La Paz, Madrid, Spain

Félix Contreras

Department of Pathology Hospital La Paz, Madrid, spain

Enrique García-Frías

Department of Pediatrics, Hospital La Paz, Madrid, Spain

M. Carmen Carrascosa

Department of Pediatrics, Hospital La Paz, Madrid, Spain

Here we report a case of neonatal lupus erythematosus syndrome presenting with multisystem organ involvement, including anemia, thrombocytopenia, purpura, bloody diarrhea, enzymatic liver abnormalities, splenomegaly and pneumonitis. These findings preceded the cutaneous rash that was the clue for the diagnosis. The patient's mother had an undiagnosed subacute cutaneous lupus erythematosus.

The various forms of onset of neonatal lupus erythematosus syndrome are emphasized.

Key Words: Neonatal lupus • SSA/Ro antibodies

Lupus, Vol. 1, No. 1, 49-50 (1991)
DOI: 10.1177/096120339100100109
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