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Lupus
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Management of Antiphospholipid Antibody Positivity and Elective Orthopedic Procedures

William M. Schnitz

Division of Rheumatology and Immunology, Oklahoma Memorial Hospital

Kathleen A. Lister

Clinical Immunology Laboratory, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, USA, Antiphospholipid Laboratory, Oklahoma Memorial Hospital

Gale A. McCarty

Arthritis/Immunology Program, Oklahoma Medical Research Foundation, Antiphospholipid Laboratory, Oklahoma Memorial Hospital

Current management of primary or secondary antiphospholipid antibody (aPL) syndromes with known embolic phenomena requiring anticoagulation is empiric in the setting of elective orthopedic procedures. Short-term withdrawal of warfarin with continuance of aspirin and glucocorticoid therapy was undertaken for sequential bilateral knee replacements in a lupus patient with aPL. Her course was successfully managed without thrombo-embolic complications.

Key Words: Antiphospholipid antibodies • Anticoagulation • Systemic lupus erythematosus • Thromboses

Lupus, Vol. 1, No. 3, 187-189 (1992)
DOI: 10.1177/096120339200100311
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