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Lupus
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Reviews

Review: Multiorgan Thrombotic Disorders in Systemic Lupus Erythematosus: A Common Link?

Ronald A. Asherson

Lupus Arthritis Research Unit, The Rayne Institute, St Thomas' Hospital, London SE1 7EH, UK

Ricard Cervepa

Systemic Autoimmune Diseases Research Unit, Department of Internal Medicine, Hospital Clínic, Barcelona, Spain

Josep Font

Systemic Autoimmune Diseases Research Unit, Department of Internal Medicine, Hospital Clínic, Barcelona, Spain

Multiorgan thrombotic disorders have been described in a variety of conditions including systemic lupus erythematosus. Among these are the 'catastrophic' antiphospholipid syndrome, disseminated intravascular coagulation and the thrombotic thrombocytopenic purpura-haemolytic uraemic syndrome. In this review we briefly analyse some specific clinical and haematological characteristics of these conditions and attempt to uncover common links between them.

Key Words: Systemic lupus • Coagulopathy • Antiphospholipid antibodies

Lupus, Vol. 1, No. 4, 199-203 (1992)
DOI: 10.1177/096120339200100402


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