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Lupus
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Reviews

Ultraviolet therapy in lupus

T P Millard

Department of Photobiology, St John's Institute of Dermatology, St Thomas' Hospital, London, UK; 57 Westfield Road, Benson, Oxfordshire OX10 6NJ, UK. Tel/Fax: 01491 838853; thomas.millard{at}kcl.ac.uk

J LM Hawk

Department of Photobiology, St John's Institute of Dermatology, St Thomas' Hospital, London, UK

This review examines the use of ultraviolet (UV) therapy in lupus erythematosus (LE), a disorder usually associated with abnormally increased photosensitivity. In addition to the abnormal cutaneous response to ultraviolet radiation (UVR) exposure, photo-aggravation of systemic disease activity in systemic LE (SLE) may also occur. However, courses of UVR exposure may also be used in the treatment or prophylaxis of various photodermatoses, and LE now appears to be included in that group. Thus, several studies have reported apparent benefits of phototherapy in both cutaneous and systemic LE, although the underlying mechanisms remain obscure and final confirmation of such efficacy is still awaited in continuing studies.

Key Words: phototherapy • photopheresis • cutaneous lupus • systemic lupus erythematosus

Lupus, Vol. 10, No. 3, 185-187 (2001)
DOI: 10.1191/096120301674565320
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