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Lupus
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Antigenic targets–workshop report

T Winkler

Section Hematopoiesis, Chair of Genetics, Fiebiger Center for Molecular Medicine, Glueckstrasse 6, Erlangen, Germany.twinkler{at}molmed.uni-erlangen.de

Several excellent animal models for systemic lupus erythematosus are available to study the pathogenetic mechanisms of anti-DNA antibodies, immunological mechanisms for their origin and the influence of susceptibility genes for the development of anti-DNA antibodies. Furthermore several transgenic mice have been generated to study B cell tolerance against DNA. During the meeting recent progress on animal models for systemic lupus erythematosuswas discussed.

Key Words: anti-DNA antibodies • (NZB£NZW)F1 • MRL lpr/lpr • B cell tolerance • susceptibility genes

Lupus, Vol. 11, No. 12, 780-782 (2002)
DOI: 10.1191/0961203302lu316oa
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