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Lupus
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What's this?

Antiphospholipid antibodies do not a syndrome make

S Stone

K Langford

C Nelson-Piercy

M A Khamashta

S Bewley

Lupus Pregnancy Clinic, Guy's and St Thomas' Hospitals Trust, London, UK

B J Hunt

Depts of Haematology and Lupus Unit, Guy'sand St Thomas' Trust, Lambeth Palace Road, London SE1 7EH, UK;Beverley.Hunt{at}gstt.sthames.nhs.uk

The association of antiphospholipid antibodies (aPLs) with a poor obstetric history and/or thrombotic event is typical of the antiphospholipid syndrome (APS). We report four cases of poor pregnancy outcome where a diagnostic label of APS resulted in delayed recognition of other causes of pregnancy loss. Pregnancy outcomes in these women were not improved with antithrombotic therapy alone. Successful outcomes were achieved only when other causes of recurrent miscarriage were considered and treated.

Key Words: antiphospholipid antibodies • fetal loss • cervical incompetence • miscarriage

Lupus, Vol. 11, No. 2, 130-133 (2002)
DOI: 10.1191/0961203302lu157xx


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APS and the brain
Lupus, December 1, 2003; 12(12): 877 - 882.
[Abstract] [PDF]



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