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Lupus
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Mycobacterium haemophilum infection in an SLE patient on mycophenolate mofetil

C L Teh

Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, 11, Jalan Tan Tock Seng, Singapore 308433 Cheng_Lay_Teh{at}ttsh.com.sg

K O Kong

Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore

A Py Chong

Department of Pathology and Laboratory Medicine, Tan Tock Seng Hospital, Singapore

H Badsha

Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore

We describe a case of Mycobacterium haemophilum in an immunocompromised patient with systemic lupus erythematosus (SLE). Mycobacterium haemophilum is a recently described pathogen which has not been previously described either in SLE patients or patients on Mycophenolate Mofetil. Mycobacterium haemophilum can be difficult to diagnose, as it may not have the granulomas characteristic of atypical mycobacterial infections. Combination therapy with at least two drugs for several months is required and the outcome depends on the patient's underlying immunocompromised state. Our report highlights the need for early diagnosis and treatment of Mycobacterium haemophilum in immunocompromised patients with SLE.

Key Words: Mycobacterium haemophilum • systemic lupus erythematosus • mycophenolic acid

Lupus, Vol. 11, No. 4, 249-252 (2002)
DOI: 10.1191/0961203302lu175cr
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