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Lupus, Vol. 12, No. 2, 140-143 (2003)
DOI: 10.1191/0961203303lu278cr

Catastrophic antiphospholipid syndrome complicating orthotopic liver transplantation

A Villamil

Liver Transplantation Unit, Hospital Italiano de Buenos Aires, agadano{at}fibertel.com.ar

E Sorkin

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

M C Basta

International Medicine B, Autoimmunity Unit, Hospital J A Fernandez, Argentina

E Mysler

International Medicine B, Autoimmunity Unit, Hospital J A Fernandez, Argentina

S Macias

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

J Pekolj

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

M Ciardullo

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

F Eleta

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

E de Santibañes

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

A Allievi

International Medicine B, Autoimmunity Unit, Hospital J A Fernandez, Argentina

A Gadano

Liver Transplantation Unit, Hospital Italiano de Buenos Aires

Catastrophic antiphospholipid syndrome (CAPS) is an acutely devastating situation characterized by widespread thrombotic microangiopathy in the presence of elevated titers of antiphospholipid antibodies. We describe a 57-year old woman who underwent liver transplantation for primary sclerosing cholangitis and developed this malignant variant of the antiphospholipid syndrome.

Key Words: anticoagulation • APS • catastrophic • catastrophic APS • orthotopic liver transplantation


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[Abstract] [Full Text] [PDF]