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Street conversations with Henry KunkelDivision of Rheumatology and Department of Immunology, University of Washington, Seattle, Washington, USA, elkon{at}u.washington.edu Nineteen eighty two was a fertile time for lupus research on York Avenue. The molecular and functional characteristics of the lupus autoantigens were being discovered by the newly introduced technologies, immunoprecipitation and western blotting. Were the antigens providing the essential clue to the cause of lupus? Was it their intracellular location? Was it their function? Was it their immunochemical structure? Were they cross-reactive with foreign antigens? Henry Kunkel discusses.
Key Words: lupus autoantibodies Ro La ribosome New York
Lupus, Vol. 12, No. 3,
170-171 (2003) |
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