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Why not work on T and NK cells in the Kunkel laboratory?

Institute of Immunology, University of Kiel, Kiel, Germany, kabelitz{at}immunologie.uni-kiel.de

Coming from Hans Wigzell’s laboratory in Uppsala, Sweden, I joined the Kunkel laboratory in 1981 to spend a post-doctoral fellowship period financed by the German Research Organization. While I initially worked with Nick Chiorazzi in an attempt to generate monoclonal antibody-secreting human B-cell hybridomas, I later studied the in vitro effects of tumor promoters on human natural killer cells and collaborated with Mary Crow on some aspects of the so-called autologous mixed lymphocyte reaction. Working in the stimulating atmosphere of the Kunkel laboratory was an exceptionalexperience.I was particularlyimpressed by the efficient organizationof clinical research at Rockefeller University. The following is a very personal resumee of my stay in the Kunkel laboratory.

Key Words: autologous mixed lymphocyte reaction • chronic lymphocytic leukemia • human monoclonal antibodies • natural killer cells • tumor promoters

Lupus, Vol. 12, No. 3, 195-199 (2003)
DOI: 10.1191/0961203303lu355xx


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