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Lupus
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Neutrophilic eccrine hidradenitis mimicking cutaneous vasculitis in a lupus patient: a complication of cyclophosphamide

D W Lienesch

Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, USA, lienesd{at}ucmail.uc.edu

D F Mutasim

Department of Dermatology, University of Cincinnati College of Medicine, Cincinnati, USA

R R Singh

Department of Medicine, University of Cincinnati College of Medicine, Cincinnati, USA

Neutrophilic eccrine hidradenitis (NEH) is an unusual self-limited skin disorder characterized by an inflammatory cell infiltrate in the deep dermis involving the eccrine sweat glands, commonly presenting as painful cutaneous nodules. NEH occurs most frequently in patients receiving chemotherapy for haematologic malignancies. We report a case of NEH masquerading as cutaneous vasculitis in a woman receiving cyclophosphamide for lupus nephritis. The association of NEH and the use of cytotoxic agents for SLE or other autoimmune diseases has not been reported previously. NEH must be considered in lupus patients receiving cytotoxic agents to avoid inappropriate use of corticosteroids or antibiotics in this self-limited condition.

Key Words: neutrophilic eccrine hidradenitis • systemic lupus erythematosus

Lupus, Vol. 12, No. 9, 707-709 (2003)
DOI: 10.1191/0961203303lu420cr
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