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Lupus
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Any increased risk of autoimmune disease?

R Cimaz

Department of Pediatrics, Istituti Clinici di Perfezionamento, Milano, Italy, rolando.cimaz{at}unimi.it

Autoimmune diseases such as systemic lupus erythematosus (SLE) are known to have a strong genetic component, therefore the risk of autoimmune disease might be increased in family members of patients with SLE. However, there are currently no data that support a higher incidence of autoimmune disorders in the offspring of SLE patients. Babies with neonatal lupus are not at increased risk to develop SLE in later life, but a continued follow-up is suggested, especially prior to adolescence and if the mother herself has an autoimmune disease.

Key Words: autoimmune • congenital heart block • neonatal lupus • offspring • pregnancy • systemic lupus erythematosus

Lupus, Vol. 13, No. 9, 736-739 (2004)
DOI: 10.1191/0961203303lu1093oa


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A Tincani, E Danieli, M Nuzzo, M Scarsi, M Motta, R Cimaz, A Lojacono, R Nacinovich, F Taddei, A Doria, et al.
Impact of in utero environment on the offspring of lupus patients
Lupus, November 1, 2006; 15(11): 801 - 807.
[Abstract] [PDF]



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