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Lupus, Vol. 14, No. 12, 959-963 (2005)
DOI: 10.1191/0961203305lu2186cr

The shrinking lung syndrome in systemic lupus erythematosus: improvement with corticosteroid therapy

K T.M Oud

Pulmonology Department, Pulmonology Department, Onze Lieve Vrouwe Hospital, Amsterdam, The Netherlands

P Bresser

Pulmonology Department

R J M ten Berge

Department of Internal Medicine, Division of Clinical Immunology & Rheumatology, Academic Medical Centre, Amsterdam, The Netherlands

R E Jonkers

Pulmonology Department, r.e.jonkers{at}amc.uva.nl

Respiratory manifestations of systemic lupus erythematosus (SLE) are frequent. The ‘shrinking lung syndrome’ (SLS) represents a rare complication of SLE. The pathogenesis and therapy of the SLS remains controversial. We report a series of five consecutive cases with the SLS of which we provide a detailed description of the extent and dynamics of the response to corticosteroid therapy.

Key Words: corticosteroids • diaphragmatic weakness • shrinking lung syndrome • systemic lupus erythematosus


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