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Lupus
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Lupus erythematosus proliferative glomerulonephritis in fetus

F Daïkha-Dahmane

Service d’Anatomie Pathologique, Unité de Foetopathologie, Hôpital de Poissy-Saint Germain en laye, site de Poissy, France, fdaikha{at}voila.fr

J P Bault

Service de Gynécologie Médico-Chirugicale et Obstétrique, Hôpital Général de Dreux, Dreux, France

D Molina-Gomes

Service d’Histo-Embryologie-Cytogénétique, Biologie de la Reproduction et Génétique Médicale

D Hillion

Service de Néphrologie, Hôpital de Poissy-Saint Germain en laye, site de Poissy, France

Y Ville

Service de Gynécologie Obstérique, Hôpital de Poissy-Saint Germain en laye, site de Poissy, France

We report the case of a fetus with proliferative glomerulonephritis in the context of maternal systemic lupus erythematosus (SLE). The pattern of the renal lesions correspond to the class III of revisited WHO classification of glomerulonephritis in SLE. Amniotic fluid analysis showed a high level of albumin and the presence of anti-Ro and anti-DNA antibodies that were possibly responsible for the renal injury.

Key Words: fetal renal injury • maternal systemic lupus erythematosus

Lupus, Vol. 14, No. 4, 326-327 (2005)
DOI: 10.1191/0961203303lu2045cr
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