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Spontaneous splenic artery hemorrhage with secondary antiphospholipid syndrome in lupus: a case report

College of Medicine at the University of Illinois at Urbana-Champaign, Urbana, IL, USA, itagaki{at}uiuc.edu

J S Gregory

Department of Surgery at Carle Foundation Hospital, Urbana, IL, USA

Spontaneous hemorrhage is a rare complication of lupus. We describe a 36-year old female with lupus who suffered spontaneous, nontraumatic hemorrhage from branches of the splenic artery with massive blood loss while being treated for a lupus flare. We compare this to the two other reported cases of similar lupus-associated splenic artery hemorrhage documented in the literature, both of which had significant pre-existing hemorrhagic risk factors. Spontaneous, nontraumatic hemorrhage of the splenic artery in the absence of risk factors, and in a patient with secondary antiphospholipid syndrome, has been previously undescribed in lupus.

Key Words: antiphospholipid • hemorrhage • lupus • splenic artery

Lupus, Vol. 14, No. 6, 479-482 (2005)
DOI: 10.1191/0961203305lu2089cr


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