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Lupus
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*Vasculitis
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ANCA-associated vasculitis as paraneoplastic syndrome with colon cancer: a case report

L Díez-Porres

Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain, jjrios{at}movistar.com

J J Ríos-Blanco

Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain, jjrios{at}movistar.com

A Robles-Marhuenda

Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain

M Gutiérrez-Molina

Department of Pathology, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain

A Gil-Aguado

Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain

J J Vázquez-Rodríguez

Department of Internal Medicine, Hospital Universitario La Paz, Universidad Autónoma de Madrid, Spain

Coexistence of a vasculitis and a neoplastic disease is rare and the pathogenesis is unknown. Most of these associations refer to leukocytoclastic or poliarteritis nodosa (PAN)-type vasculitis and hematological malignancies. There are few reports of vasculitis in patients with solid tumours and there are also few reports of paraneoplastic ANCA-associated vasculitis. We report a case of p-ANCA-positive vasculitis with peripheral nerve involvement associated with a colon cancer. Vasculitis resolved after corticoid treatment and surgical removal of the tumour.

Key Words: ANCA • colonic neoplasms • vasculitis

Lupus, Vol. 14, No. 8, 632-634 (2005)
DOI: 10.1191/0961203305lu2153cr
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