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Lupus
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Ocular manifestations of systemic lupus erythematosus: a clinical review

V Peponis

Department of Ophthalmology, General Hospital of Piraeus ‘Tzaneion’, Greece, Department of Pharmacology, Medical School, University of Athens, Greece

V C Kyttaris

Department of Cellular Injury, Walter Reed Army Institute of Research, Silver Spring, MD, USA, vasileios.kyttaris{at}na.amedd.army.mil

C Tyradellis

Department of Ophthalmology, General Hospital of Piraeus ‘Tzaneion’, Greece

I Vergados

2nd University Eye Clinic, Medical School, University of Athens, Greece

N M Sitaras

Department of Pharmacology, Medical School, University of Athens, Greece

Although the eye itself is regarded an ‘immune-privileged’ organ, systemic lupus erythematosus (SLE) can affect every ocular structure, leading, if left untreated, to significant visual loss or even blindness. Since ocular inflammation in SLE can antedate the diagnosis of the systemic disease and cause significant morbidity, prompt diagnosis and treatment of the underlying systemic autoimmune disease is imperative.

Key Words: antimalarials • keratoconjunctivitis sicca • retina • scleritis • systemic lupus erythematosus

Lupus, Vol. 15, No. 1, 3-12 (2006)
DOI: 10.1191/0961203306lu2250rr
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