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Socioeconomic status in systemic lupus erythematosus

Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

M Petri

Department of Medicine, Division of Rheumatology, Johns Hopkins University of Medicine, 1830E Monument Street, Suite 7500, Baltimore, MD 21205, USA; mpetri{at}jhmi.edu

Our understanding of the biological pathogenesis of systemic lupus erythematosus (SLE) is rapidly expanding. Although biologic research is vital, studies that address the importance of socioeconomic factors that contribute to the causation of the outcome of SLE are necessary to understand the full scope of the disease.

Studies of social factors in SLE usually include ethnicity, gender and socioeconomic status (SES) as categorical variables. One hypothesis is that these variables exert their effect through a biologic or genetic factor. However, there is growing evidence to suggest a more direct psychological or sociological impact of these variables on disease. Although in research studies it may be difficult to tease out the biological and sociological impacts of these variables, the eventual understanding of these diverse roles will help in the design of eventual therapeutic interventions.

Key Words: socioeconomic status • systemic lupus erythematosus • ethnicity • survival

Lupus, Vol. 15, No. 11, 720-723 (2006)
DOI: 10.1177/0961203306070008


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