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Lupus, Vol. 15, No. 12, 886-888 (2006)
DOI: 10.1177/0961203306071431

Primary lymphoma of CNS, mycophenolate mofetil and lupus

P F Finelli

Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, USA, pfinell{at}harthosp.org

K Naik

Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, USA

J A DiGiuseppe

Department of Pathology and Laboratory Medicine, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, USA

A Prasad

Department of Neurology, Hartford Hospital and University of Connecticut School of Medicine, Hartford, CT, USA

Lymphoproliferative disorders are known to complicate immunosuppressive therapy and two cases of primary lymphoma of CNS (PCNSL) have previously been described in association with mycophenolate mofetil (MMF) treatment. We report the third case of PCNSL in a patient with lupus nephropathy while on MMF treatment. PCNSL may be seen more frequently considering the increased use of MMF in immunosuppressant responsive conditions.

Key Words: systemic lupus erthematosus • primary lymphoma of CNS • mycophenolate mofetil • immunosuppressive therapy


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