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Neuromyelitis optica (Devic’s syndrome) as first manifestation of systemic lupus erythematosus

Department of Neurology, University of Heidelberg, Heidelberg, Germany, christian_jacobi{at}med.uni-heidelberg.de

K Stingele

Department of Neurology, University of Schleswig-Holstein Campus Kiel, Kiel, Germany

R Kretz

Department of Neurology, Charité Campus Virchow Clinic, Berlin, Germany

M Hartmann

Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany

B Storch-Hagenlocher

Department of Neurology, University of Heidelberg, Heidelberg, Germany

A Breitbart

Department of Internal Medicine, University of Ulm, Ulm, Germany

B Wildemann

Department of Neurology, University of Heidelberg, Heidelberg, Germany

Neurologic symptoms rarely occur as presenting feature of systemic lupus erythematosus (SLE). We describe a 37-year old woman who presented with several episodes of transverse myelitis and optic neuritis. Clinical, radiologic and laboratory findings were compatible with neuromyelitis optica (NMO). Seven years after disease onset clinical and laboratory findings were diagnostic for SLE. This case illustrates that NMO may represent a first manifestation of SLE for many years.

Key Words: CNS • neuromyelitis optica • systemic lupus erythematosus

Lupus, Vol. 15, No. 2, 107-109 (2006)
DOI: 10.1191/0961203306lu2265cr


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