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Lupus, Vol. 15, No. 7, 431-435 (2006)
DOI: 10.1191/0961203306lu2329oa
© 2006 SAGE Publications

Use of Proteomics in Analysis of Autoimmune Diseases

Y Xiang

Department of Bioregulation and Proteomics, Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan

T Kato

Department of Bioregulation and Proteomics, Institute of Medical Science, St Marianna University School of Medicine, Kawasaki, Kanagawa, Japan, t3kato{at}marianna-u.ac.jp

Autoimmune diseases are common by diseases characterized by disorders of immune responses and autoimmune impairment involving multiple tissues, organs and systems. The autoantigens (Ags)/autoantibodies (Abs) are not only hallmarks but also involved in pathogenesis of autoimmune diseases. In recent years, proteomics technologies have been used and demonstrated effective in searching new Ags/Abs as well as disease biomarkers in autoimmune diseases.

Key Words: autoantibody/autoantigen • autoimmune diseases • biomarker • proteomics


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