SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Lupus
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Ben-Ami, D
Right arrow Articles by Shoenfeld, Y
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ben-Ami, D
Right arrow Articles by Shoenfeld, Y
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Stenosis in Antiphospholipid Syndrome: A New Finding with Clinical Implications

D Ben-Ami

Department of Medicine ‘B’ and Center for Autoimmune Diseases, Sheba Medical Center (affiliated to Tel-Aviv University), Israel

E Bar-Meir

Department of Plastic and Reconstructive Surgery, Sheba Medical Center, Israel

Y Shoenfeld

Department of Medicine ‘B’ and Center for Autoimmune Diseases, Sheba Medical Center (affiliated to Tel-Aviv University), Israel, Yehuda.Shoenfeld{at}sheba.health.gov.il

Antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by a variety of clinical manifestations. Recent studies suggest arterial stenosis is involved in APS. Furthermore, arterial stenosis may be a relevant and treatable cause for hypertension, renal, CNS and gastrointestinal manifestations of APS. Our objective was to overview the published data regarding arterial stenosis in APS-the clinical presentation, diagnosis, suggested therapies and the possible mechanisms. We searched PUBMED (1951-2006) reference lists for the role of arterial stenosis in APS. APS patients might present with arterial stenosis. Its recognition has important diagnostic and therapeutic implications. Articles suggest that anticoagulation treatment with INR above three may reverse the artery stenosis and achieve subsequent clinical improvement. Currently, there are no specific guidelines for the management of APS patients with arterial stenosis. The exact mechanism of arterial stenosis in APS patients remains unclear.

Key Words: anticoagulation • antiphospholipid syndrome • hypertension • intra-cranial • renal artery stenosis • stenosis

Lupus, Vol. 15, No. 7, 466-472 (2006)
DOI: 10.1191/0961203306lu2335oa
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 CJASNHome page
H. Wu, D. J. Birmingham, B. Rovin, K. V. Hackshaw, N. Haddad, D. Haden, C.-Y. Yu, and L. A. Hebert
D-Dimer Level and the Risk for Thrombosis in Systemic Lupus Erythematosus
Clin. J. Am. Soc. Nephrol., November 1, 2008; 3(6): 1628 - 1636.
[Abstract] [Full Text] [PDF]

Home page
 Rheumatology (Oxford)Home page
C. Christodoulou, S. Sangle, and D. P. D'Cruz
Vasculopathy and arterial stenotic lesions in the antiphospholipid syndrome
Rheumatology, June 1, 2007; 46(6): 907 - 910.
[Abstract] [Full Text] [PDF]


Advertisement