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Lupus
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Acute granulomatous lupus pneumonitis: the first case report

S Chaiamnuay

Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA; sumapac{at}yahoo.com

L W Heck

Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA

W C Bell

Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA

H M Bastian

Division of Clinical Immunology and Rheumatology, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA

Acute lupus pneumonitis is a rare form of pulmonary involvement in systemic lupus erythematosus (SLE). We present herein a patient with acute lupus pneumonitis who presented with acute onset of fever, cough, dyspnea and a miliary pattern on chest radiographs and computer tomography. Lung histopathology revealed bronchocentric granulomatosis. To our knowledge, this is the first documented case of granulomas in lung parenchyma believed to be caused by SLE. The differential diagnoses of acute lupus pneumonitis and the pertinent literature are discussed.

Key Words: granulomas • pneumonitis • systemic lupus erythematosus

Lupus, Vol. 16, No. 3, 201-204 (2007)
DOI: 10.1177/0961203306076222
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