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Lupus, Vol. 16, No. 7, 525-528 (2007)
DOI: 10.1177/0961203307079461

Intravascular lymphoma in a patient with systemic lupus erythematosus: a case report

D. Sánchez-Cano

Unidad de Enfermedades Autoinmunes Sistémicas, Hospital Clínico San Cecilio, Granada, Spain, danisanchezcano{at}supercable.es

JL Callejas-Rubio

Unidad de Enfermedades Autoinmunes Sistémicas, Hospital Clínico San Cecilio, Granada, Spain

A. Vilanova-Mateu

Servicio de Dermatología, Hospital Clínico San Cecilio, Granada, Spain

M. Gómez-Morales

Servicio de Anatomía Patológica, Hospital Clínico San Cecilio, Granada, Spain

N. Ortego-Centeno

Unidad de Enfermedades Autoinmunes Sistémicas, Hospital Clínico San Cecilio, Granada, Spain

Intravascular lymphoma IVL is a rare and aggressive disorder characterized by proliferation of large lymphoid cells (most commonly B-cells) within the lumen of small vessels of nearly every organ. Obliteration of vessels leads to the different clinical signs, being cutaneous lesions and neurological signs the most frequent presentations, whereas lymph node and reticuloendothelial system involvement is typically absent.1—4 No association with SLE has been described up to the present. We report a case of IVL in a patient with systemic lupus erythematosus (SLE) involving skin, central nervous system (CNS) and bone marrow. Lupus (2007) 16, 525—528.

Key Words: B-cell lymphoma • intravascular lymphoma • systemic lupus erythematosus


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W. Ishii, S. Ito, Y. Kondo, H. Tsuboi, M. Mamura, D. Goto, I. Matsumoto, A. Tsutsumi, T. Sumida, Y. Okoshi, et al.
Intravascular Large B-Cell Lymphoma With Acute Abdomen As a Presenting Symptom in a Patient With Systemic Lupus Erythematosus
J. Clin. Oncol., March 20, 2008; 26(9): 1553 - 1555.
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