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Lupus
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Reviews

Review: Contraception in adolescents with systemic lupus erythematosus

A. Tincani

Department of Rheumatology and Clinical Immunology, Brescia Hospital and University of Brescia, Brescia, Italy, tincani{at}bresciareumatologia.it

M. Nuzzo

Department of Rheumatology and Clinical Immunology, Brescia Hospital and University of Brescia, Brescia, Italy

A. Lojacono

Department of Obstetrics and Gynecology, Brescia Hospital and University of Brescia, Brescia, Italy

M. Cattalini

Department of Pediatric Immunology and Rheumatology, Pediatric Clinic, University of Brescia, Brescia, Italy

A. Meini

Department of Pediatric Immunology and Rheumatology, Pediatric Clinic, University of Brescia, Brescia, Italy

In the management of adolescents with systemic lupus erythematosus (SLE), sexual activity and prevention of unwanted pregnancies are important topics. Many contraceptive methods are available nowadays. Oral contraceptives (OCs) are the preferred choice among adolescents in general. However, the use of these medications in adolescents with SLE raises serious concerns, particularly the risk of thrombotic events from estrogen exposure and the impact of these medications on lupus activity. In this article, different contraceptive methods available are reviewed and their application in adolescents with SLE is discussed. In conclusion, OCs are the methods of choice in adolescents with stable disease and no antiphospholipid antibodies (aPL) detected. In patients with aPL, fewer options are available, and the selection of the preferred form of contraception should be made on an individual basis. Lupus (2007) 16, 600—605.

Key Words: antiphospholipid antibodies • contraception • oral contraceptives • systemic lupus erythematosus

Lupus, Vol. 16, No. 8, 600-605 (2007)
DOI: 10.1177/0961203307078074
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