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Lupus, Vol. 16, No. 8, 663-669 (2007)
DOI: 10.1177/0961203307077539

Reviews

Review: Quality of life in children with systemic lupus erythematosus: a review

LN Moorthy

Division of Pediatric Rheumatology, Robert Wood Johnson Medical School-UMDNJ, Department of Pediatrics, New Brunswick, NJ, USA, LNMoorthy{at}mac.com

Mge Peterson

Hospital For Special Surgery, New York, NY, USA

MJ Harrison

Weill Cornell Medical College, Hospital For Special Surgery, New York, NY, USA

KB Onel

Division of Pediatric Rheumatology, Robert Wood Johnson Medical School-UMDNJ, Department of Pediatrics, New Brunswick, NJ, USA, La Rabida Children's Hospital, The University of Chicago, La Rabida Children's Hospital, Chicago, IL, USA

Tja Lehman

Division of Pediatric Rheumatology, Robert Wood Johnson Medical School-UMDNJ, Department of Pediatrics, New Brunswick, NJ, USA, Hospital for Special Surgery, Weill Medical College of Cornell University; Division of Pediatric Rheumatology, Hospital for Special Surgery, New York, NY, USA

Systemic lupus erythematosus (SLE) in children is a chronic multisystem disease with wide ranging effects on their quality of life (QOL). While SLE's impact on different arenas of life and well-being has been extensively examined in the adult population, its effect on children has not received adequate attention. This review discusses the multidimensional aspect of QOL, the biopsychosocial implications of SLE, factors complicating QOL measurement in the affected population, and the different generic and disease-specific scales used for measuring QOL and related constructs. Until now, there have not been any pediatric SLE-specific health-related QOL (HRQOL) scales. A section is devoted to a novel instrument developed specifically for measuring QOL in pediatric lupus called the Simple Measure of the Impact of Lupus Erythematosus in Youngsters© (SMILEY©). SMILEY© is a brief, easily understood, valid, reliable and internally consistent pediatric SLE-specific QOL scale and will be a useful adjunct to clinical trials and outcomes research. Lupus (2007) 16, 663—669.

Key Words: pediatric • quality of life • systemic lupus erythematosus


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