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Lupus
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case-report

Cerebellar ataxia in systemic lupus erythematosus

S Appenzeller

Department of Medicine, Rheumatology Unit, Faculty of Medical Sciences, PO Box 6111 University of Campinas – UNICAMP, Zip Code 13083-970, Campinas, SP, Brazil

F Cendes

Department of Neurology, Faculty of Medical Sciences, PO Box 6111 University of Campinas – UNICAMP Zip Code 13083-970, Campinas, SP, Brazil

LTL Costallat

Department of Medicine, Rheumatology Unit, Faculty of Medical Sciences, PO Box 6111 University of Campinas – UNICAMP, Zip Code 13083-970, Campinas, SP, Brazil

Neuropsychiatric manifestations are commonly observed in systemic lupus erythematosus (SLE) patients; however, cerebellar involvement has rarely been reported. In the presence of acute cerebellar ataxia, etiologies related (focal edema and ischemia) and not related (infections, malignancy and paraneoplastic syndromes) to lupus have to be considered and they imply different treatment strategies. We report the clinical and radiological features of 3 SLE patients who presented with acute cerebellar ataxia. A review of the literature was performed by documenting cases of cerebellar ataxia in SLE and the importance of neuroimaging in the evaluation of these patients.

Key Words: cerebellar ataxia • MRI • SLE

Lupus, Vol. 17, No. 12, 1122-1126 (2008)
DOI: 10.1177/0961203308093071
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