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Lupus, Vol. 17, No. 7, 676-678 (2008)
DOI: 10.1177/0961203307088291

case-report

Adalimumab-induced lupus erythematosus

JM Martín

Department of Dermatology, Hospital Clínico Universitario, Valencia, Spain; Dermatology Unit, Hospital Quirón, Valencia, Spain, jmmart{at}eresmas.com

JM Ricart

Dermatology Unit, Hospital Quirón, Valencia, Spain

J Alcácer

Department of Pathology, Hospital Quirón, Valencia, Spain

N Rausell

Department of Pathology, Hospital Quirón, Valencia, Spain

G Arana

Dermatology Unit, Hospital Quirón, Valencia, Spain

Adalimumab, an anti-tumour necrosis factor agent, especially used in the treatment of rheumatoid arthritis, has a good safety profile. One of the most common side-effects of adalimumab is the development of autoantibodies. Despite the induction of autoantibodies, the clinical presentation of immune-mediated complications upon adalimumab therapy, including a lupus-like syndrome, is very rare. We have recently evaluated a new case of adalimumab-induced lupus erythematosus.

Key Words: adalimumab • drug-induced lupus erythematosus • leflunomide


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