This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Web of Science (1) Citing Articles via Scopus Google Scholar Articles by Avcin, T PubMed PubMed Citation Articles by Avcin, T Social Bookmarking                         What's this?

The Ped-APS Registry: the antiphospholipid syndrome in childhood

T Avin

Department of Allergology, Rheumatology and Clinical Immunology, University Children’s Hospital, University Medical Center Ljubljana, Ljubljana, Sloveniatadej.avcin{at}kclj.si

R Cimaz

Meyer Hospital and University of Florence, Florence, Italy

B Rozman

Department of Rheumatology, University Medical Center Ljubljana, Ljubljana, Slovenia

The Ped-APS Registry Collaborative Group*

In recent years, antiphospholipid syndrome (APS) has been increasingly recognised in various paediatric autoimmune and nonautoimmune diseases, but the relatively low prevalence and heterogeneity of APS in childhood made it very difficult to study in a systematic way. The project of an international registry of paediatric patients with APS (the Ped-APS Registry) was initiated in 2004 to foster and conduct multicentre, controlled studies with large number of paediatric APS patients. The Ped-APS Registry is organised as a collaborative project of the European Forum on Antiphospholipid Antibodies and Juvenile Systemic Lupus Erythematosus Working Group of the Paediatric Rheumatology European Society. Currently, it documents a standardised clinical, laboratory and therapeutic data of 133 children with antiphospholipid antibodies (aPL)-related thrombosis from 14 countries. The priority projects for future research of the Ped-APS Registry include prospective enrolment of new patients with aPL-related thrombosis, assessment of differences between the paediatric and adult APS, evaluation of proinflammatory genotype as a risk factor for APS manifestations in childhood and evaluation of patients with isolated nonthrombotic aPL-related manifestations.

Key Words: Keywords: antiphospholipid antibodies • antiphospholipid syndrome • paediatrics

Lupus, Vol. 18, No. 10, 894-899 (2009)
DOI: 10.1177/0961203309106917


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				R Cervera and A Tincani European Working Party on Systemic Lupus Erythematosus and European Forum on Antiphospholipid Antibodies: two networks promoting European research on autoimmunity Lupus, September 1, 2009; 18(10): 863 - 868. [PDF]