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Antiphosphatidylethanolamine antibodies and the antiphospholipid syndromeLaboratoire d’Immunologie, Hôpital de La Conception. Marseille, Francemsanmarco{at}ap-hm.fr
Service d'Hématologie, Hopital Jean Verdier, Assistance Publique, Hôpitaux de Paris, Bondy, France The antiphospholipid antibodies included as laboratory criteria of the antiphospholipid syndrome (APS) are antibodies reacting with anionic phospholipids – anticardiolipin antibodies and lupus anticoagulant – and with β2-glycoprotein I. However, antibodies reacting with phosphatidylethanolamine (aPE), a zwitterionic phospholipid, have also been described to be associated with the main features of APS. The objectives of this review are to describe the characteristics of aPE and to bring attention to recent evidence that aPE are correlated with the main clinical features of APS, notably, in the absence of the laboratory criteria of this syndrome.
Key Words: antiphosphatidylethanolamine antibodies • antiphospholipid antibodies • antiphospholipid syndrome • recurrent foetal losses • thrombosis
Lupus, Vol. 18, No. 10,
920-923 (2009) This article has been cited by other articles:
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