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Gigantomastia and autoimmunity: a case report

Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

LY McGirt

Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA

R Abuav

Department of Dermatology, Johns Hopkins Medical Institutions, Baltimore, Maryland, USArnussba4{at}jhmi.edu

Gigantomastia is a rare breast condition characterised by diffuse, rapid, and excessive breast hypertrophy that can result in symptoms ranging from pain to necrosis and sepsis. It typically occurs in the setting of marked hormonal changes such as puberty and pregnancy. Rarely, gigantomastia has been reported to develop in the setting of an autoimmune illness. We present a case of gigantomastia developing in a patient with systemic lupus erythematosus, who was treated with methotrexate and bilateral mammoplasty.

Key Words: breast hypertrophy • gigantomastia • pregnancy • systemic lupus erythematosus

Lupus, Vol. 18, No. 11, 1015-1018 (2009)
DOI: 10.1177/0961203309105362


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