This Article Full Text (PDF) All Versions of this Article: 0961203309106829v1 18/14/1316    most recent References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Scopus Google Scholar Articles by Kano, O. Articles by Iwasaki, Y. PubMed PubMed Citation Articles by Kano, O. Articles by Iwasaki, Y. Social Bookmarking                         What's this?

Limbic encephalitis associated with systemic lupus erythematosus

Department of Neurology, Methodist Neurological Institute, Houston, Texas, USA, osamukano{at}aol.com, Department of Neurology, Aikawa Hospital, Japan

K. Arasaki

Department of Neurology, Aikawa Hospital, Japan

K. Ikeda

Department of Neurology, Toho University Omori Medical Center, Tokyo, Japan

J. Aoyagi

Department of Neurology, Toho University Omori Medical Center, Tokyo, Japan

H. Shiraishi

First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

M. Motomura

First Department of Internal Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan

Y. Iwasaki

Department of Neurology, Toho University Omori Medical Center, Tokyo, Japan

A 34-year-old woman with systemic lupus erythematosus (SLE) presented with general fatigue, seizures and memory loss. Magnetic resonance imaging of the brain showed a high signal area in the mesial temporal lobe bilaterally. Computed tomography scan of the chest and abdomen and ultrasound of pelvis detected no malignancy and tumour marker, antibodies to antineuronal antibodies (anti-Hu, anti-Ta and anti-Ma) and antibodies to voltage-gated potassium channels were all negative. The present case is limbic encephalitis (LE) associated with SLE and the pathogenesis may include autoimmunity shared. Our experience indicates that the immunologic spectrum of LE will expand to include additional immune mechanisms. Lupus (2009) 18, 1316—1319.

Key Words: limbic encephalitis • magnetic resonance imaging • systemic lupus erythematosus • voltage-gated potassium channel antibody

This version was published on December 1, 2009

Lupus, Vol. 18, No. 14, 1316-1319 (2009)
DOI: 10.1177/0961203309106829


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?