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Lupus
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case-report

Mycobacterium tuberculosis-specific immunospot assay of pleural exudate mononuclear cells is useful for the exclusion of tuberculous pleuritis in patients with lupus pleuritis

K Takase

Yokohama City University Medical Center, Center for Rheumatic Diseases, Yokohama, Japan

S Ohno

Yokohama City University Medical Center, Center for Rheumatic Diseases, Yokohama, Japan

H Ideguchi

Yokohama City University Medical Center, Center for Rheumatic Diseases, Yokohama, Japan

S Murakami

Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan

M Takeno

Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan

Y Ishigatsubo

Department of Internal Medicine and Clinical Immunology, Yokohama City University Graduate School of Medicine, Yokohama, Japan

It is often difficult to make a diagnosis of pleuritis associated with rheumatic diseases because of lack of specific diagnostic tools. We report a patient with lupus pleuritis from which tuberculous pleuritis was distinguished by Mycobacterium tuberculosis-specific enzyme-linked immunospot assay of pleural exudate mononuclear cells. After the diagnosis of lupus pleuritis, the patient was successfully treated with prednisolone.

Key Words: enzyme-linked immunospot assay (ELISPOT) • lupus pleuritis • tuberculous pleuritis

Lupus, Vol. 18, No. 2, 175-177 (2009)
DOI: 10.1177/0961203308094998
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