This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by Gordon, C Articles by Hughes, G Search for Related Content PubMed PubMed Citation Articles by Gordon, C Articles by Hughes, G Social Bookmarking                         What's this?

European consensus statement on the terminology used in the management of lupus glomerulonephritis

Rheumatology Research Group, Division of Immunity and Infection, University of Birmingham and Departments of Rheumatology, City Hospital, Sandwell and West Birmingham Hospitals NHS Trust and University Hospital Birmingham NHS Foundation Trust, Birmingham, UK

D Jayne

Department of Medicine, School of Clinical Medicine, University of Cambridge, UK

C Pusey

Renal Section, Division of Medicine, Imperial College London, Hammersmith Hospital, London, UK

D Adu

Department of Nephrology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK

Z Amoura

Internal Medicine Department, French National Reference Center for Systemic Lupus, Pitie-Salpetriere Hospital, Paris, France

M Aringer

Division of Rheumatology, Department of Medicine III, University Clinical Center Carl Gustav Carus at the Technical University of Dresden, Germany

J Ballerin

Nephrology Department, Fundacio Puigvert, Barcelona, Spain

R Cervera

Department of Autoimmune Diseases, Hospital Clinic, Barcelona, Spain

J Calvo-Alén

Rheumatology Section, Hospital General Sierrallana, Torrelavega, Spain

C Chizzolini

Immmunology and Allergy, University Hospital and School of Medicine, Geneva, Switzerland

JM Dayer

Faculty of Medicine, University of Geneva, Switzerland

A Doria

Division of Rheumatology, University of Padova, Padova, Italy

F Ferrario

Renal Immunopathology Centre, Department of Nephrology, San Carlo Borromeo Hospital, Milan, Italy

J Floege

Medizinische Klinik II, Aachen, Germany

L Guillevin

Department Internal Medicine, Hospital Cochin, Assistance PUblique Hopitaux de Paris,Paris, France

M Haubitz

16 Department of Nephrology, Medical School Hannover, Hannover, Germany

F Hiepe

17 Clinic for Rheumatology and Clinical Immunology, Charite Universitatsmedizin Berlin, Germany

F Houssiau

18 Rheumatology Department, Universite Catholique de Louvan, Brussels, Belgium

P Lesavre

19 Service de Nephrologie, Hopital Necker, Paris, France

L Lightstone

20 Renal Section, Division of Medicine, Imperial College London, Hammersmith Campus, UK

PL Meroni

21 Allergy and Clinical Immunology Unit, Department of Internal Medicine, University of Milan, IRCCS Istituto Auxological Italiano, Milan, Italy

O Meyer

22 Service de rheumatologie, Hopital Bichat, Paris, France

B Moulin

23 Nephrology Department, CHU Strasbourg, France

K O’Reilly

24 Apreva Pharmaceuticals, Surrey, UK

M Praga

25 Hospital 12 de Octubre, Madrid Hospital Virgen de Rocio, Seville, Hospital Gregorio Maranon, Madrid, Spain

H Schulze-Koops

26 Nikolaus Fiebiger Centre for Molecular Meidcine, University of Erlangen-Nuremberg, Erlangen, Germany

RA Sinico

27 Clinical Immunology Unit and Renal Unit, Azienda Ospedaliera Ospedale San Carlo Borromeo, Milan, Italy

KGC Smith

28 Cambridge Institute for Medical Research, University of Cambridge, Addenbrooke’s Hospital, Cambridge, CB2 OXY

A Tincani

29 Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Italy

C Vasconcelos

30 Imunologia Clinica, Hospital Geral Santo Antonio, Universidade do Porto, Porto, Portugal

G Hughes

31 London Lupus Centre, London Bridge Hospital, London, UK londonlupuscentre{at}hcahealthcare.co.uk

Systemic lupus erythematosus (SLE) is a complex, multisystem autoimmune disorder, which often involves referral to multiple medical specialists. Lupus nephritis (LN) occurs in ~35% of adults with SLE and predicts poor survival. There is currently no consensus on how to manage patients with SLE or LN across specialties and across different European countries. The Lupus Nephritis Terminology Advisory Group was formed to address this issue as it impacts upon LN treatment. It has developed consensus statements based on opinions from expert panel meetings with nephrologists, nephropathologists, rheumatologists, clinical immunologists and internal medicine specialists from many European countries, after reviewing current guidelines from the European League Against Rheumatism, the American College of Rheumatology and the participants’ experience. In this article, we report consensus statements that were developed in six important areas: classification of patients with LN, how classification affects the selection of treatment options and definitions of induction, response, flare and maintenance. We have also proposed a consensus for the terminology involved in the management of LN that is consistent with clinical opinion gathered from multidisciplinary expert meetings and with existing guidelines. We believe this consensus approach provides agreed expert opinion to clinicians and will form the basis for optimising LN treatment.

Key Words: European consensus statement • lupus nephritis • terminology

Lupus, Vol. 18, No. 3, 257-263 (2009)
DOI: 10.1177/0961203308100481


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?

This article has been cited by other articles:

				G. M. N. Daleboudt, I. M. Bajema, N. N. T. Goemaere, J. M. van Laar, J. A. Bruijn, and S. P. Berger The clinical relevance of a repeat biopsy in lupus nephritis flares Nephrol. Dial. Transplant., July 21, 2009; (2009) gfp359v1. [Abstract] [Full Text] [PDF]