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Lupus
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brief-report

Chloroquine –Induced Hair Depigmentation

TB Di Giacomo

Department of Dermatology, Hospital das Clínicas, University of Sao Paulo, Sao Paulo, Brazil

NYS Valente

Department of Dermatology, Hospital das Clínicas, University of Sao Paulo, Sao Paulo, Brazil

MMS Nico

Department of Dermatology, Hospital das Clínicas, University of Sao Paulo, Sao Paulo, Brazil

A case of hair depigmentation induced by chloroquine diphosphate subacute overdosage in an 11-year-old patient with dermatomyositis is presented. Normal coloured hair growth occurred after normalisation of chloroquine dosage. A discussion on possible pathomechanisms of this phenomenon is made based on experimental data and previously reported patients with the same condition.

Key Words: chloroquine • depigmentation • hair

Lupus, Vol. 18, No. 3, 264-266 (2009)
DOI: 10.1177/0961203308097473
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