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Lupus
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case-report

Noonan syndrome associated with systemic lupus erythematosus

MP Lisbona

Unitat de Reumatologia, Hospital de Sabadell, Institut Universitari Parc Taulí (UAB), Sabadell (Barcelona), Spain

M Moreno

Unitat de Reumatologia, Hospital de Sabadell, Institut Universitari Parc Taulí (UAB), Sabadell (Barcelona), Spain

C Orellana

Unitat de Reumatologia, Hospital de Sabadell, Institut Universitari Parc Taulí (UAB), Sabadell (Barcelona), Spain

J Gratacos

Unitat de Reumatologia, Hospital de Sabadell, Institut Universitari Parc Taulí (UAB), Sabadell (Barcelona), Spain

M Larrosa

Unitat de Reumatologia, Hospital de Sabadell, Institut Universitari Parc Taulí (UAB), Sabadell (Barcelona), Spain

Noonan syndrome (NS) is a developmental disorder characterised mainly by cardiac defects and craniofacial dysmorphia. An association between NS and some autoimmune diseases, such as thyroiditis and systemic lupus erythematosus (SLE), has been suggested. We report the case of a 28-year-old man with a diagnosis of NS and autoimmune hypothyroidism who developed symptoms and immunologic features of SLE.

Key Words: autoimmune thyroiditis • Noonan syndrome • systemic lupus erythematosus

Lupus, Vol. 18, No. 3, 267-269 (2009)
DOI: 10.1177/0961203308094996
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