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Successful treatment of massive ascites with intraperitoneal administration of a steroid in a case of systemic lupus erythematosus

Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China

XB Yang

Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China

FF Hou

Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, Chinaffhou{at}public.guangzhou.gd.cn

X Zhang

Division of Nephrology, Nanfang Hospital, Southern Medical University, Guangzhou, China

Massive ascites is a rare manifestation of systemic lupus erythematosus (SLE) and has a poor response to glucocorticoid therapy, probably because of impaired vascular circulation due to persistent peritoneal inflammation. We describe a young woman presenting with massive painless ascites as the predominant manifestation of SLE. Peritoneal effusion was resistant to the oral administration of steroids and the conventional therapies for ascites. Intraperitoneal injection of triamcinolone, an insoluble glucocorticoid, induced dramatic remission of massive ascites, with no adverse event or recurrence.

Key Words: massive ascites • systemic lupus erythematosus • therapy

Lupus, Vol. 18, No. 8, 740-742 (2009)
DOI: 10.1177/0961203308099709


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