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Lupus
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Anticardiolipin Syndrome, Aspirin Therapy and Fetal Malformation

K. Chakravarty

Department of Rheumatology, Norfolk & Norwich Hospital, Brunswick Road, Norwich, UK

P. Merry

Department of Rheumatology, Norfolk & Norwich Hospital, Brunswick Road, Norwich, UK

A patient with systemic lupus erythematosus and elevated cardiolipin antibody levels was given low-dose aspirin therapy prior to and throughout her third pregnancy to minimize the risk of miscarriage. She delivered a boy at 38 weeks with the skeletal deformity of two thoracic hemivertebrae. The putative role of aspirin causing this birth defect is discussed.

Key Words: SLE • Anticardiolipin syndrome • Aspirin • Fetal malformation

Lupus, Vol. 2, No. 1, 61-62 (1993)
DOI: 10.1177/096120339300200111
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