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Lupus
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Hepatic Infarction in a Pregnant Patient with the 'Primary' Antiphospholipid Syndrome

A. Millan-Mon

Department of Internal Medicine, N Sra de La Candelaria Hospital, Santa Cruz de Tenerife

J.L. Porto

Department of Internal Medicine; Juan Canalejo Hospital, La Coruña Spain

C. Novo

Department of Internal Medicine; Juan Canalejo Hospital, La Coruña Spain

C. Garcia-Martin

Department of Internal Medicine; Juan Canalejo Hospital, La Coruña Spain

D. Guitian

Department of Pathology, Juan Canalejo Hospital, La Coruña Spain

We describe a patient with previous venous thrombosis while using oral contraceptives and recurrent pregnancy loss, who presented with massive hepatic infarction in the last trimester of the fourth gestation. Thrombocytopenia, the lupus anticoagulant (LA) and the anticardiolipin antibody (aCL) were detected and a diagnosis of a 'primary' antiphospholipid syndrome (APS) was made. The clinical and histological manifestations and the differential diagnosis, especially with DIC and pre-eclampsia, are discussed.

Key Words: Recurrent fetal loss • Hepatic infarction • 'Primary' antiphospholipid syndrome • Disseminated intravascular coagulation • Pre-eclampsia

Lupus, Vol. 2, No. 1 suppl, 275-279 (1993)
DOI: 10.1177/096120339300200117
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