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Clinical Profile of Chinese Patients with Systemic Lupus Erythematosus
S.S. Lee
Medical A Unit, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong
C.S. Li
Medical A Unit, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong
P.C.K. Li
Medical A Unit, Queen Elizabeth Hospital, Wylie Road, Kowloon, Hong Kong
In the 9-year period between 1982 and 1991, 137 patients attending a medical clinic of Queen Elizabeth Hospital, Hong Kong, were diagnosed as having systemic lupus erythematosus according to the American Rheumatism Association's criteria for classification. The female-to-male ratio was 16 to 1. Commonly the onset age was between 20 and 40. Malar rash (70%), arthritis (70.8%) and nephropathy (69.3%) were the most common manifestations. Antinuclear factor was invariably positive, whereas anti-extractable nuclear antigen antibodies were positive in varying degrees—Sm 12.7%, nRNP 28.8%, Ro 60.2%, La 8.4%. There were 22 deaths during the follow-up period, two-thirds from active diseases. Gastro-intestinal bleeding and opportunistic infection were common complications.
Key Words: Systemic lupus erythematosus • Chinese • Autoantibodies
Lupus, Vol. 2, No. 2,
105-109 (1993)
DOI: 10.1177/096120339300200207
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