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A Simple Severity of Disease Index for Systemic Lupus Erythematosus

Department of Medicine, Division of Rheumatic Diseases, University of Connecticut School of Medicine, Farmington, Connecticut 06030, USA

Jean-Luc Senegal

Department of Medicine, Rheumatic Disease Unit, Notre-Dame Hospital, University of Montreal School of Medicine, Montreal, Canada

Charles Rivest

Department of Medicine, Rheumatic Disease Unit, Notre-Dame Hospital, University of Montreal School of Medicine, Montreal, Canada

Jean-Richard Goulet

Department of Medicine, Rheumatic Disease Unit, Notre-Dame Hospital, University of Montreal School of Medicine, Montreal, Canada

Naomi Rothfield

Department of Medicine, Division of Rheumatic Diseases, University of Connecticut School of Medicine, Farmington, Connecticut 06030, USA

Although indices of activity for systemic lupus erythematosus have been developed and validated, a disease staging system requires the measurement of severity as well. We have constructed such a scale, the Lupus Severity of Disease Index (Lupus SDI). Accepted clinical, pathologic and physiologic classification schemes were employed to validate this index at two separate research institutions. The Lupus SDI allows homogenization of patient populations for the purposes of research and, possibly, for case mix adjustment.

Key Words: Severity of disease • Systemic lupus erythematosus • Validation • Index • Staging

Lupus, Vol. 2, No. 2, 119-123 (1993)
DOI: 10.1177/096120339300200210


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