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Lupus
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Parkinson-Like Symptoms as a Manifestation of Systemic Lupus Erythematosus

Yoshinori Miyoshi

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Tatsuya Atsumi

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Hirohiko Kitagawa

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Nobutaka Ogura

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Yoshiharu Amasaki

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Akito Tsutsumi

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Katsunori Ohnishi

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Atsushi Fujisaku

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Akira Sagawa

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

Takao Koike

Department of Medicine , Hokkaido University School of Medicine, Sapporo 060, Japan

A 42-year-old Japanese woman with systemic lupus erythematosus (SLE) developed Parkinsonian-like movements. Steroid pulse therapy was most effective and additional anti-Parkinsonian drugs were not required. Although psychosis, seizures and meningitis are common central nervous system (CNS) manifestations in SLE patients, Parkinsonian-like symptoms are extremely rare. The putative genesis and treatment of CNS lupus are discussed.

Key Words: Systemic lupus erythematosus • CNS lupus • Parkinson-like symptoms • Steroid pulse therapy

Lupus, Vol. 2, No. 3, 199-201 (1993)
DOI: 10.1177/096120339300200314
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