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Lupus, Vol. 4, No. 3, 172-175 (1995)
DOI: 10.1177/096120339500400302


Reviews

Occasional Review: Use of hyperbaric oxygen in rheumatic diseases: case report and critical analysis

D.J. Wallace

Department of Medicine. Cedars-Sinai Medical Centre, UCLA School of Medicine. Los Angeles, CA

S. Silverman

UCLA School of Medicine. Los Angeles, CA

J. Goldstein

The Chronic Fatigue Syndrome Institute, Anaheim, CA

D. Hughes

The Hyperbaric Oxygen Institute, San Bernardino, CA, USA

Hyperbaric oxygen has been used in patients with rheumatic disease for many years without reports of untoward or unusual complications for a variety of non-rheumatic indications. Recent evidence that hyperbaric oxygen inhibits the actions of certain cytokines, acts as an immune modulator and may help cognitive dysfunction has resulted in a re-examination of its potential role in rheumatic diseases. A case report of a lupus/scleroderma crossover patient is presented whose cognitive dysfunction improved after hyperbaric oxygen therapy. The history of hyperbaric oxygen and its physiology are related, along with a focused review of its effects on the immune and central nervous systems. Areas which might warrant further consideration by rheumatologists are outlined, as well as areas of concern.

Key Words: hyperbaric oxygen • scleroderma • rheumatic diseases


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