SAGE Journals Online
Advertisement
Sign In to gain access to subscriptions and/or personal tools.

 

Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Advertisement

Sign In to gain access to subscriptions and/or personal tools.
Lupus
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by Lagana', B.
Right arrow Articles by Bonomo, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lagana', B.
Right arrow Articles by Bonomo, L.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Heart rate variability and cardiac autonomic function in systemic lupus erythematosus

B. Lagana'

Department of Medicina Clinica, University La Sapienza, Rome, Italy, V.le dell'Universitá, 37-00185 Rome, Italy

L. Tubani

Department of Medicina Clinica, University La Sapienza, Rome, Italy

N. Maffeo

Department of Medicina Clinica, University La Sapienza, Rome, Italy

C. Vella

Department of Medicina Clinica, University La Sapienza, Rome, Italy

E. Makk

Department of Medicina Clinica, University La Sapienza, Rome, Italy

L. Baratta

Department of Medicina Clinica, University La Sapienza, Rome, Italy

L. Bonomo

Department of Medicina Clinica, University La Sapienza, Rome, Italy

The cardiac autonomic function was evaluated in 23 patients with Systemic Lupus Erythe matosus (SLE) without clinical expression of dysautonomia and in 14 healthy volunteer subjects as a control group, by analysis of Heart Rate Variability (HRV) from 24 h ambula tory electrocardiography. All the patients were taking corticosteroids and 10 of them also Ciclosporin A (CsA). The following parameters of HRV were performed: Time domain: standard deviation of the RR intervals average (SDNN) and percentage of RR adjacent intervals differing from each other more than 50 msec (pNN50). Frequency domain: low frequencies (LF) and high frequencies (HF).

Significant lower values were detected in SLE patients vs controls: SDNN = 69.40 vs 127.72; pNN50 = 16.44 vs 25.95; LF = 8.34 vs 34.97; HF = 3.21 vs 12.18. The incidence of autonomic dysfunction in our SLE population evaluated by considering intervals of nor mality is approximately 78% for SDNN; 17% for pNN50; 91% for LF and, finally, 56% for HF. The analysis of HRV may be a valuable technique in the study of the incidence of dysautonomia for these patients.

Key Words: Lupus • dysautonomia • heart rate variability

Lupus, Vol. 5, No. 1, 49-55 (1996)
DOI: 10.1177/096120339600500110
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 ANGIOLOGYHome page
B. Lagana, O. Schillaci, L. Tubani, R. Gentile, R. Danieli, R. Coviello, L. Baratta, F. Scopinaro, and B. Lagana
Lupus Carditis: Evaluation with Technetium-99m MIBI Myocardial SPECT and Heart Rate Variability
Angiology, February 1, 1999; 50(2): 143 - 148.
[Abstract] [PDF]


Advertisement