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Post-partum dilated cardiomyopathy in anti-phospholipid positive woman

° Department of Obstetrics and Gynecology

O. Eid

° Department of Obstetrics and Gynecology

C. Tosetto

Cardiology Unit, ICP, Milano

PL Meroni

Istituto di Medicina Interna, Malattie Infettive and Immunopatologia, University of Milan

Recurrent fetal loss and pregnancy complications, especially severe early-onset preeclamp sia, are frequently associated with anti-phospholipid antibodies. We report a case of post- partum cardiac involvement leading to dilated cardiomyopathy in a woman with a persistent positivity for anti-cardiolipin and anti-nuclear antibodies. Her clinical and obstetric record reported two previous fetal losses but no other signs characteristic of the anti-phospholipid syndrome or diagnostic for a systemic lupus erythematosus. Post-partum cardiomyopathy might be another cardiac presentation of the anti-phospholipid syndrome, in addition to the well known valvular involvement. In patients with persistent positivities for anti-phospholipid antibodies, a prompt identification of such a complication in the post- partum period should be taken into account by physicians. Adequate cardiologic treatment associated with antiaggregant and steroid therapy might be useful to prevent further com plications in these patients.

Key Words: Anti-cardiolipin antibodies • Post-partum cardiomyopathy • Anti-phospholipid syndrome

Lupus, Vol. 5, No. 3, 247-250 (1996)
DOI: 10.1177/096120339600500315


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