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Lupus
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Medline Plus Health Information
*Joint Disorders
*Salivary Gland Disorders
*Sjogren's Syndrome
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What's this?

Anti-Ro(SS-A) antibody positive Sjögren's/lupus erythematosus overlap syndrome

TT Provost

The Johns Hopkins University School of Medicine, Department of Dermatology, Baltimore, Maryland

R. Watson

St. James Hospital, Dublin, Ireland

E. Simmons-O'Brien

The Johns Hopkins University School of Medicine, Baltimore, Maryland

Unlike anti-Ro(SS-A) antibody positive subacute cutaneous lupus erythematosus (SCLE) patients, anti-Ro(SS-A) antibody positive lupus patients with Sjögren's syndrome (SS/LE) appear to have a more guarded prognosis. Our studies indicate these SS/LE patients have an increased frequency of pulmonary, neurological, and renal disease compared to SCLE patients.

Key Words: Sjögren's syndrome • lupus erythematosus • anti-Ro(SS-A) antibodies • renal • neurologic and pulmonary disease

Lupus, Vol. 6, No. 2, 105-111 (1997)
DOI: 10.1177/096120339700600205


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A N Scofield, B T Kurien, T P Gordon, and R H Scofield
Can B cell epitopes of 60 kDa Ro distinguish systemic lupus erythematosus from Sjogren's syndrome?
Lupus, August 1, 2001; 10(8): 547 - 553.
[Abstract] [PDF]



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