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Lupus
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Subclinical multisystemic autoimmunity presenting as a progressive myelopathy

G. Linardaki

Department of Pathophysiology, Laiko General Hospital, School of Medicine, National University of Athens

FN Skopouli

Department of Pathophysiology, Laiko General Hospital, School of Medicine, National University of Athens

C. Koufos

Department of Pathophysiology, Laiko General Hospital, School of Medicine, National University of Athens

HM Moutsopoulos

Department of Pathophysiology, Laiko General Hospital, School of Medicine, National University of Athens

Autoimmunity can manifest clinically in many ways; however, despite the various efforts to classify autoimmune disorders into specific disease entities, the borders between these disorders remain, in many cases, unclear.

In this report we describe a young woman with subclinical Sjögren's syndrome and biliary cirrhosis, who presents clinically with symptoms exclusively from the central nervous system. This neurological syndrome is consistent with a progressive myelopathy. Although the patient has a serologically and histologically confirmed multisystemic autoimmune disorder, she fulfills none of the classification criteria for the diagnosis of a specific connective tissue disease.

Key Words: subclinical • autoimmunity • myelopathy

Lupus, Vol. 6, No. 8, 675-677 (1997)
DOI: 10.1177/096120339700600809
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