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Systemic lupus erythematosus in Kuwait—hospital based study

Department of Medicine, Faculty of Medicine, Kuwait University; Kuwait; Mubarak Al-Kabeer Hospital; Kuwait

A Al-Awadi

H Siddiqui

I Al-Salim

Amiri Hospital, Ministry of Health, Kuwait

D Shehab

Department of Medicine, Faculty of Medicine, Kuwait University; Kuwait; Mubarak Al-Kabeer Hospital; Kuwait

I Umamaheswaran

Department of Medicine, Faculty of Medicine, Kuwait University; Kuwait

S Gaurer

Mubarak Al-Kabeer Hospital; Kuwait

K Al-Saied

R Kumar

Department of Medicine, Faculty of Medicine, Kuwait University; Kuwait

A N Malaviya

Department of Medicine, Faculty of Medicine, Kuwait University; Kuwait; Mubarak Al-Kabeer Hospital; Kuwait

The present study describes the clinical characteristics of patients with systemic lupus erythematosus (SLE), from the rheumatology service of the two main teaching hospitals in Kuwait. It was a retrospective-cum-prospective clinical study of 108 SLE patients. There were 98 females and 10 males, with a median age of 31.5 y. Kuwaitis constituted 69%, while 31% were expatriates. The mean disease duration was 62 months. The main clinical features were: musculoskeletal involvement (87%), photosensitivity (48%), malar rash (43%), discoid lesions (10%), oral ulcers (33%), vasculitic skin lesions (10%), haematological features (53%), constitutional symptoms (51.4%), neuropsychiatric manifestations (23%), renal involvement (37%), serositis (29%), clinical manifestations of antiphospholipid syndrome (21%), cardiac involvement (10%) and pulmonary manifestations (19%). In conclusion, the clinical features of SLE in Kuwait were similar to most major studies from developed countries. Main differences included prominent haematological and mucocutaneous manifestations and possibly a low prevalence of anti-Sm antibodies. Whether these differences are due to the environment or genetic factors, remains to be studied.

Key Words: systemic lupus erythematosus • autoimmunity • Kuwait

Lupus, Vol. 7, No. 7, 434-438 (1998)
DOI: 10.1191/096120398678920389


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