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Exacerbation of systemic lupus erythematosus related to cytomegalovirus infection

Department of Medicine, Jutendo University Izu-Nagaoka Hospital, 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka 410–22, Tokyo 113, Japan

S Lee

H Ogasawara

Department of Internal Medicine and Rheumatology, Tokyo 113, Japan

I Sekigawa

Department of Internal Medicine, Jutendo University Izu-Nagaoka Hospital, 1129 Nagaoka-cho, Izu-Nagaoka, Tagata-gun, Shizuoka 410-22, Japan

N Iida

Department of Medicine, Jutendo University Izu-Nagaoka Hospital, 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka 410–22, Tokyo 113, Japan

Y Tomino

Department of Nephrology, Jutendo University School of Medicine, 2-1-1 Hongo, Bunkyo-ku, Tokyo 113, Japan

H Hashimoto

Department of Internal Medicine and Rheumatology, Tokyo 113, Japan

S Hirose

Department of Medicine, Jutendo University Izu-Nagaoka Hospital, 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka 410–22, Tokyo 113, Japan

We report two patients with systemic lupus erythematosus (SLE) in whom cytomegalovirus (CMV) infection may have played a significant role in the exacerbation or onset of symptoms. The first patient had thrombocytopenia and the second had proteinuria. CMV infection was observed in both patients when their symptoms developed.

Key Words: systemic lupus erythematosus • cytomegalovirus • thrombocytopenia • proteinuria • viral Meningitis

Lupus, Vol. 7, No. 8, 561-564 (1998)
DOI: 10.1191/096120398678920596


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