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A case of SLE with acute, subacute and chronic cutaneous lesions successfully treated with Dapsone

Rheumatology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy

M Mosca

Clinical Immunology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy

E Bernacchi

Dermatology Unit, University of Florence, Florence, Italy

S Bombardieri

Clinical Immunology Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy

We describe a patient with systemic lupus erythematosus (SLE) who exhibited severe cutaneous involvement characterized by the simultaneous presence of acute, subacute and discoid lesions in association with anti-Sl antibodies. After she failed to respond to chloroquine, medium to low dose steroids, steroid pulses, retinoids and cyclophosphamide, the patient was treated with Dapsone and a dramatic improvement in the cutaneous lesions was seen after only one month.

Key Words: acute • subacute and discoid lupus • Dapsone

Lupus, Vol. 8, No. 3, 240-243 (1999)
DOI: 10.1191/096120399678847713


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